Science can be wondrous, beguiling, clumsy, right and wrong. The word science comes from the Latin “scientia,” meaning knowledge, and both artists and scientists are searching for the same knowledge: an understanding about the world and how we inhabit it. The two cultures have very different methodologies – scientist’s strict protocols, reductionist ethos and a remit to maximise objectivity by abnegating the human element, whilst the artist’s perspective is speculative, imaginative and anthropocentric. The reliance on research, analysis, questioning and evaluation is shared, but the language of scientists gives the impression of intellectual gravitas, yet the theories and paradigms remain unstable: a set of beliefs in flux. The frameworks we all seek to expand our knowledge of the world, literally and metaphysically, conjoin in structures questioning what is reality. The search for coherence and verification regarding this universal quest for ‘a truth’ is a preoccupation of both disciplines.